The Wiitles
“The world’s first and only Wii remote rock band.”
The Wiitles are a rock band which uses Nintendo Wiimotes as their instruments. The Wiimotes are used to control the software Max/MSP, a graphical development environment, for creating music. No “real” instruments are used during the Wiitles performances.
I think RP said it best in the comments of the CNN article on the band, “To me, this group represents the death of music.”